The Nanotechnology Research Center has partnered with Early Warning, Inc. to fabricate a sensor for detection of biohazards in water.
The biosensor platform technology has been licensed to Early Warning by NASA and was originally designed with the intent to detect
pathogens in remote space environments. Each target pathogen has its own working electrode which contains bioprobes of single strands
of nucleic acids attached to the tips of the ultrasensitive carbon nanofibers. When the single strands of RNA from the sample come into
contact with the bioprobes, complementary strands hybridize into double helices. A potential scan is applied and guanine oxidation causes
a flow of electrons that is conducted by the nanowires. A ruthenium mediator amplifies the signal. These signals are calibrated with known
values and can indicate the concentration levels of the target pathogen. The carbon nanofibers are grown in an Aixtron Black Magic CVD
system using a substrate patterned with 100 nm diameter catalysts. The catalysts are fabricated with a JEOL JBX-9300FS electron beam
lithography system using a liftoff process with polymethyl methacrylate resist.
https://mediaspace.gatech.edu/media/devinbrown/1_uqrn62wg
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